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Ziac

Indications

Beta-blockers decrease the force and rate of heart contractions, thus lowering blood pressure.
Diuretics help your body produce and eliminate more urine, which also helps lower blood pressure.
Ziac combines a beta-blocker (bisoprolol) with a thiazide diuretic (hydrochlorothiazide).
Ziac is indicated for the treatment of high blood pressure and management of edema.
Ziac is indicated to treat high blood pressure.

Dosage

The usual starting dose is 2.5mg of bisoprolol with 6.25mg of Ziac once a day.
The dose may be increased every 14 days up to a maximum of 20mg bisoprolol/12.5mg Ziac once a day.

Overdose

Symptoms of overdose may include:
- Weakness;
- Vomiting;
- Thirst;
- Slow or rapid heartbeat;
- Shock;
- Nausea;
- Low blood sugar;
- Low blood pressure;
- Impaired consciousness;
- Fluid or electrolyte loss;
- Drowsiness;
- Dizziness;
- Difficult or labored breathing;
- Decreased or increased urination;
- Cramps in the calf muscle;
- Convulsions;
- Congestive heart failure;
- Confusion;
- Coma;
- Abnormal skin sensations;

Side Effects

More common side effects may include:
- Fatigue;
- Dizziness;

Brand Names

Other synonyms:
- Vetidrex;
- Urodiazin;
- Timolide;
- Thlaretic;
- Thiuretic;
- Thiaretic;
- Servithiazid;
- Ro-Hydrazide;
- Panurin;
- Newtolide;
- Neoflumen;
- Neo-Codema;
- Nefrix;
- Moduretic;
- Megadiuril;
- Maschitt;
- Lotensin Hct;
- Jen-Diril;
- Ivaugan;
- Idrotiazide;
- Hypothiazide;
- Hypothiazid;
- Hydrozide;
- Hydrothide;
- Hydrosaluric;
- Hydropres;
- Hydro-Diuril;
- Hydrodiuretic;
- Hydro-Aquil;
- Hydril;
- Hidrotiazida;
- Hidroronol;
- Hidrochlortiazid;
- Hidril;
- Fluvin;
- Esimil;
- Esidrex;
- Drenol;
- Diu-Melusin;
- Disalunil;
- Direma;
- Dicyclotride;
- Diclotride;
- Dichlotride;
- Dichlotiazid;
- Dichlorotride;
- Dichlorosal;
- Cidrex;
- Chlorzide;
- Chlorosulthiadil;
- Capozide;
- Caplaril;
- Bremil;
- Aquarius;
- Aquarills;
- Apresazide;
- Aldoril;
- Acuretic;

Contraindications

Ziac is contraindicated if you have:
- A slow heartbeat;
- Bronchial asthma;
- Certain types of irregular heartbeat;
- Inadequate blood supply to the circulatory system (cardiogenic shock);
- Severe congestive heart failure;
- Trouble urinating;

Vytorin is contraindicated if you have an allergic reaction to the drug.

Ziac Interactions

Do not take Ziac with any of the following drugs:
- Alcohol, barbiturates, or narcotics;
- Antidiabetic drugs;
- Cholestyramine and colestipol resins;
- Corticosteroids, acth;
- Lithium;
- Non-steroidal anti-inflammatory drugs;
- Other antihypertensive drugs;
- Pressor amines (norepinephrine);
- Skeletal muscle relaxants, nondepolarizing (tubocurarine);

Possible electrolyte variations and arrhythmias:
- Digoxin;
- Digitoxin;
- Deslanoside;