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Abacavir

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Indications

Abacavir belongs to a class of drugs known as nucleoside reverse transcriptase inhibitors-NRTI.
Abacavir is an antiretroviral medicine.
Abacavir is indicated in combination with other anti-HIV drugs for the treatment of HIV infection.
Abacavir is indicated with other medications to help control your HIV infection, thereby improving your quality of life.
Abacavir is indicated with other medicines to treat HIV.
Abacavir is not a cure for HIV infection, and it does not prevent the spread of HIV to others through sexual contact or blood contamination (such as sharing used needles).
Abacavir is not a cure for HIV.
Abacavir may also lower your risk of complications from HIV (such as new infections, cancers).
Abacavir will not stop the spread of HIV to others.

Contraindications

Abacavir is contraindicated if you have any of the following conditions:
- an unusual or allergic reaction to Abacavir, other medicines, foods, dyes, or preservatives;
- breast-feeding;
- liver disease;
- pregnant or trying to get pregnant;
- a serious (sometimes fatal) allergic reaction;
- a severe (sometimes fatal) liver;
- blood problem (lactic acidosis);
- if you are allergic to Abacavir;
- if you have alcohol use;
- if you have any other allergies;
- if you have kidney problems;
- if you have liver problems (such as hepatitis B or C, or cirrhosis);
- lactic acidosis (such as rapid breathing, drowsiness, muscle aches);
- symptoms of liver problems (such as dark urine, persistent nausea/vomiting, stomach/abdominal pain, yellowing eyes/skin);

Interactions

Do not take Abacavir with any of the following drugs:
- methadone;
- any other medicine that contains Abacavir;
- alcohol or alcohol containing products;

Side Effects

Abacavir side effects that you should report to your health care professional or doctor as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue;
- breathing problems, cough;
- Diarrhea;
- Difficulty breathing;
- Difficulty sleeping;
- fever or chills, sore throat;
- Fever;
- headache;
- Liver failure;
- Loss of appetite;
- Metabolic disturbance (lactic acidosis);
- nausea, vomiting, unusual stomach upset or pain;
- Nausea;
- Pancreatitis;
- redness, blistering, peeling or loosening of the skin, including inside the mouth;
- Severe allergic reactions;
- Skin rash;
- Swelling;
- trouble sleeping;
- unexplained weight loss;
- unusually weak or tired;
- Vomiting;
- Weakness;
- weight gain around waist, back, or thinning of face, arms, legs;

Form

Reported Abacavir overdose symptoms are:
- Tablets: 300 mg;
- Oral solution 20 mg/ml;

Dosage

Children (3 months and older) should receive 8 mg/kg twice daily, and the maximum recommended dose is 300 mg twice daily.
The recommended dose for adults is 300 mg twice daily or 600 mg once daily.